TNBC refers to any breast cancer that does not express the genes for the 3 most common breast cancers, namely,
Estero gen receptor (ER),
progesterone receptor (PR) and HER2/neu. TNBC is more difficult to treat because most hormone therapies target one of the 3 receptors.
Triple-negative here hs a medical meaning. Triple-negative here does not mean an added negative to a double-negative.
Triple-negative
breast cancer has a
relapse pattern that is different from hormone-positive breast
cancers.