1. A game where the only opponents are two people playing against each other.
2. Also know as speedballing; a mixture of cocaine and herion, most often injected.
1. Jack says to Tommy, "Let's play a game of one on one"
2. After getting out of lock-up, I said to myself, "I'm 'bout ready to head downtown and gets me a one on one!!"
By Carmela
One On One
san francisco bay area slang for a combination of cocaine and heroin, aka a "speedball". a hit of tar heroin and powder cocaine sold together on the street for $10 to $20.
if youre in a san francisco neighborhood such as the mission, and you hear a guy calling out "one on oners, one on oners", hes not challenging you to a game of basketball.
Friend 1: I thought you were going one on one with her.
Friend 2: Naw, man. I don't want togive up the other pussy.
By Lucinda
One On One
The phrase that people say that suck at everything but is the best in their little village where they live when they lose in a team-based. Normally followed by a really bad yo momma joke.
John: God dude, you really suck at everything.
Gaylord: what, you wanna go one on one, because I'm in your mom's bed.
John: (pause) Wow... really?
In paintball, when a player on one team and a player on the other team mark (shoot) each other at the same time, therfore resulting in a "one for one", one player is eliminated with another player from the opposing team.
Larry ran to bunker Steve and Steve shot Larry as Larry shot Steve. The ref couldn't tell who shot first, so he called a one for one.