Something that is so
disagreeable with your spirit that it feels like its existence might
negate yours.
This goes further than "hate," and implies that you and the object in question are sworn enemies.
Can be used seriously or, more likely, exaggerated for
comedic effect.
Wearing socks with sandals is the bane of my existence.
The
iPhone's autocorrect is the bane of my existence.
Stephanie's hair is the bane of my existence.