Define 2s Meaning

2S
2S means two-spirit.
Two-spirit people (also two spirit or twospirit) is a modern umbrella term used by some indigenous North Americans for gender variant individuals in their communities. Non-Native anthropologists have historically used the term berdaches for individuals who fulfill one of many mixed gender roles in First Nations and Native American tribes, but this term has more recently fallen out of favour.

"Are you a boy or a girl?"
"I'm two-spirit or 2S."
By Stepha
1s And 2s
1s and 2s are turntables(or decks)which have been the weapon of choice for djs such as dj premier of the xecutioners, mixmaster mike,dj babu of dialated peoples, and many more.....

hey man u cumin the club my boi is on the 1s and 2s tonight
By Irena
2 2s
2 2s
A Toronto way of saying honestly

Yo 2 2s your cheesing me fam, come off my line

Yo 2 2s that baddie has a fat ass
By Lindsey
Sonic Adventure 2s
A unit of measurement (money) based of the games price.

Them: Bro I just got a $6000 PC, it's epic
You: you do realise that you could've bought 1000 sonic adventure 2s right?
Them: shit
By Britte
Plus Twos (Plus 2s)
Plus Twos (2s) are the slang name for breast implants. The term “Plus Two (2s)” has 2 meanings, 1) the implants usually result in an increase of 2 cup sizes, 2) the women who receive Plus 2s technically and typically though not always, would be rated by their male counter parts as being 2 points higher on the proverbial 1 to 10 scale.

Dude, I saw Tara at the club on Friday, she dropped 10 pounds and got a set of Plus Twos (Plus 2s) now she is a 7 instead of a 5 and I would do her after a 6 pack.

My boyfriend dumped me for a chick with Plus Twos (Plus 2s) I think it may be time to make an appointment for a set.
By Kyle