Define Brain Hurt Meaning

to manipulate ,confound or to "mindfuck" someone.

a mild headache caused by someone confusing or acting abnormally towards you.
or
caused when you don't know how to talk to someone because they are so different from you

When someone says this that means they feel like they are going to cry but don’t know how to say it. They want you to ask if they are ok and give them attention. Go up and immediately give them a hug,

to cause pain to the brain . or to cause pain to the cerebral cortex