When someone has been taking drugs for so long that their brain is fried and they look like a washed upjunkie. Not to be confused with stoners.
John: Hey man, the other day I ran into that guy Joe who we went to school with.
Jack: Oh yeah, how is he?
John: Not too good. He's totally drug-fucked.
Jack: That sucks.
By Brooke
Drug Fucking
Ingesting very large amounts of overthe counter drugs, or common prescriptions, in order to achieve symptoms of overdose or drug reactions. A cheap but very dangerous way to get high.
yeah, man, I went drug fucking last night, took 15 asprins, caffeine, claratin, a sleeping pill or 2, some robitussin, nyquill, and some tylenol.