Define Drug Fucked Meaning

Drug-fucked
When someone has been taking drugs for so long that their brain is fried and they look like a washed up junkie. Not to be confused with stoners.

John: Hey man, the other day I ran into that guy Joe who we went to school with.
Jack: Oh yeah, how is he?
John: Not too good. He's totally drug-fucked.
Jack: That sucks.
By Brooke
Drug Fucking
Ingesting very large amounts of overthe counter drugs, or common prescriptions, in order to achieve symptoms of overdose or drug reactions. A cheap but very dangerous way to get high.

yeah, man, I went drug fucking last night, took 15 asprins, caffeine, claratin, a sleeping pill or 2, some robitussin, nyquill, and some tylenol.
By Donetta
Drug Fucked
When someone has taken drugs for so long that they are immune to getting that high.

Girl 1: How long have you been on drugs?
Girl 2: For 25 years. Do you think i'm drug fucked?
Girl 1: Damn, i hope not. That sucks.
By Jobie