Define E621 Meaning

a website mostly made out of NSFW furry artwork, there are some SFW but everyone ignores them

It is also home to a lot of cursed artworks

a place where can find a lot of furry porn and be able to sort by many different categories like if you were looking at rule 34

e621 is an image board focused on furry artwork as well as other fetish art.. Do you know what furries are? You should.

Much of the content is pornographic in nature, and it contains many hardcore fetishes. Its cleaner counterpart is e926.

One of the Seven Circles of internet Hell, where furries and other stains on humanity flock. Some call it the off-brand rule34, while for others this is their most-visited site. Usually used as a gallery for both NSFW and SFW art. Porn posted here typically is composed of ponies, anthromorphic animals with human features, cartoons and various video game characters, ranging from Ankha from Animal Crossing to Ren & Stimpy. Some more well-known characters are : Various Pokemon, MLP characters and even Deathclaws from the Fallout series. Art is organized by tags that tell one or more things in the image. e621 is also home to porn that takes things to the extreme.

e621 is a furry artwork site that is mainly known for it's furry NSFW, or yiff. Commonly used in memes as well.

It's the E number for Monosodium Glutamate (aka MSG).

The furry imageboard with the same name most likely named itself E621 to address how 'tasty' their content is.

Funnily enough, there's a forum named E926 (the E number for bleach) that exists as an eye-bleach after one views the 'tasty' content of E621.

E-number for Monosodium Glutamate, a common food additive that has a distinct umami taste.

Also refers to a particular website...

A large online community of furries (and others but mostly furries) that contains SFW art and tonnes of NSFW art.

A sin.