Goku and Vegeta used the
potara earrings to become Vegito. Then, Vegito kicked the shit out of Buu-Han until Buu-Han ate Vegito and he defused because of Buu's stomach acids.
Goku and Vegeta fused again to anal Zamasu. They pulled off a Final Kamehameha before they defused because the writers wanted Trunks to use the Spirit to defeat Zamasu.
Cauliflia and Kale used the potara earrings to become
Kefla so they could defeat Goku until he went ultra instinct and wiped
Kefla's ass.