American
Moon rocket and holds the record for highest payload capacity of any functional rocket ever built. The Soviet N1 was designed to compete with it.
Its payload to Low Earth Orbit was the
unempty S-IVB (third) stage, the LM or Landing Module, and the Apollo CSM. The third stage would then restart to perform translunar injection.
The Saturn V, throughout its launches, has never failed and no crew have died from it. (On Apollo 13, the fault was with the Service Module and not
the Saturn V.)
The Saturn V also cost over
a billion dollars per launch though, so...
Not to be confused with the
Saturn IB, which used the same S-IVB but as a second stage. The Saturn IB was never intended to land astronauts on the Moon.