when a situation calls for a response where a more pronounced explative does not quite apply. or when a situation is noticed where simply saying shit is not enough and requires special recognition.
jamie: help, i can't seem to find my vibrator.
dan: i think shelly must have broken it or ran down the batteries again.
shelly: OH FOR SHIT'S SAKE!
By Stephannie
For Shit Sakes
An expression of total discussed in someone as to why they cannot do something, and you feel as if they can at least do it for the sake of a piece of shit if nothing else at all matters.
Dad: Son, please take out the trash for your mother.
Son: But why? It is not like I have to do what you say and you can’t make me!
Dad: Well for shit sakes, you could at least do something around the house every now and then!