the comparison of hitting someone with a combination or flurry of punches, usually 2 or 3 hits, with a personal fried chicken meal of the same number of pieces.
Because a 2 or 3 pc. meal usually includes a biscuit (among other things like a side dish), "with a biscuit" makes reference to this indirectly. This exclamatory term was coined by MaSTASoLIDUS, and is usually used in multiplayer action games, or while watching anything where a person/party is hit with a combo of punches.
Sometimes contracted to just 'biscuit' or 'the biscuit'.