Eric: Hey man, remember in the 40-year-old virgin when Dave said, "Do you know how I know you're gay?..."
Tom: 'Cause you saw Rentthree times.
By Marquita
40 Year Old Virgin
1)A movie made in 2005 and starringSteve Carell about a 40 year old man who is a virgin and his friends keep trying to help him lose it, very very funny.
2)Insulting term (mainly used by men) meaning that a person is such a loser that they could never get laid.
2)"Dude, your such a fuckin'loser! you'll never get any pussy! you're gonna be the 40 year old virgin"