The results after
copious amounts of drugs have been consumed.
You no longer have a
grasp of reality and are acting high and crazy. Commonly used in relation to amphetamines, cocaine and similar
"I just had six lines of coke and a hit on that
crackpipe, I am off my box mate."
He was
slumped on the toilet, chewing his gums and drooling. Clearly he was off his box.
"
You shit yourself in public? You must have been off your box."