To completely screw up something; kill a joke; maliciously kill a story; to say something completely unrelated to the discussed topic; being oblivious to everything; to heed the progress of something; etc.
Marcojoe'd it when he attempted to make an alteration of a joke but completely and miserably failed
By Marcelle
Joe'd
When you're extremely high but there's people nearby so you use it as a code word
To get so messed up in a weekend that you find a video of yourself on youtube running for vice president and doing shirtless pushups on a very busy street corner.