Define Can't Handle It Meaning

Being put to the test and resulting in failure.

phrase that typically describes a situation that encompasses one or many of the following emotions:
1. a feeling of overwhelming intensity(usually sexual)
2. a recalled memory of grandeur
3. a moment of enormous success
4. a description of beauty or repulsiveness
5. a moment of great frustration(usually sexual)

Expression first popularised by Jack Nicholson in the character of Col. Nathan R. Jessep in A Few Good Men (1992, dir. Rob Reiner), when he blows up in court in Tom Cruise's face. Handy exclamation to direct at the computer screen when somebody votes down an eminently rational definition on urbandictionary. Parodied by Sideshow Bob in an episode of The Simpsons ("Pish! I deride your truth-handling abilities!").

when you're unable to manipulate something put into your possessions or unable to control someone or something into a stable range of management.

other interpretations:
you can't handle this
you can't handle it

When a "self-proclaimed rapper" gets high, then pissed off and tries to rhyme the words "brawl" and "ruckus," the words must be changed into words that don't exist, thus, "Don't bring the brawl if you can't handle the ruckus" becomes "Don't bring the brullox if you can't handle the rullex."

My brother Johnathan, given a million opportunities and chances in life, yet still setup for failure because of plain stupidity and drug addiction.

Not being able to handle a particular situation due to it being to much for the person.