A french expression meaning "kill the sack." During the French Revolution, many scrotums were accidentally amputated by the guillotine. These scrotums would then land on some soft cheese and mutate into horrible monsters that would scurry about the streets of France. If you came across one, it would pounce on you and bite your neck, causing you to scream "Kill the sack! Kill the sack!" At that point it was the end of the road for you. Which is why we now use the term cul-de-sac to describe a dead end in the road.
the place in a woman's vagina which is the spot where you can't go in any further whether with an inanimate object or a penis.
"I was doing her last night and I hit her cul de sac which made her screamin pain."
By Coretta
Cul De Sac
A girl at a bar or other drinking establishment who you think you're getting somewhere with, but things unceremoniously end, leaving you alone for the night.
Ron: "Dude, that girl turned out to be a real Cul De Sac. I thought I was getting somewhere and then I just had to turn around."