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Define On One Meaning

On One
Just generally trippin', tweakin', weird, actin' a fool, blackin' out, goin' off. Not necessarily due to drugs, though that's the obvious reference.

Homie was on one, just buggin' like I shot his mom or something.
By Emiline
On One
to be under the influence of methamphetamines

i heard joe's been on one for the past three days
By Aile
On One
Feeling way too good.

Just broke up with my girl and this alone time has me feelin' on one right now.
By Elwira
On One
To be under the influence of methamphetamines AKA ice,meth,speed,dope,etc.

Tuttie's on one man, he been smokin' ice all week!
By Lorena
On One
to be high, faded, to have just smoked weed.

My man James was on one at the party.
By Ainslee
On One
horny randy upforit madforit gaggingforit right-on-it etcetc

see above
By Drucy
One On One
BASKETBALL, where you (and only you) play against one other person

I played against Santiago in a one on one basketball game
By Molly
One On One
An informal code of street fighting, not allowing bystanders to interfere in the fight.

Hey bitch-ass, let's square it up one-on-one in the midldle of the street!
By Janean
One And One
a bag of heroin and coke together.

i wanted to do a speedball so i told my connect i need a "one and one" bag.
By Modesty
The One One
The person that makes you change everything you said you wouldn't ; put it down in every way ; the one you meant to be with ; time enough : able to control without force ; Mesmerizing

Boooooyyyyyyyy, You the one one!
By Lissy