1) v.t. Neuroadapted.
One is "zapped" when he is depressed on account of being elated at an earlier time.
Explanation:
There is an idea in neurochemistry that the proliferation of pleasure causing neurotransmitters (i.e.
dopamine) will actually decrease one's sensitivity to those neurotransmitters (because organisms tend to maintain
homeostasis. There various physiological mechanisms. The presence of dopamine, for instance, probably downregulates the dopamine receptor in the post-synaptic
neuron, upregulates the enzymes that break down dopamine in the
synapse, and upregulates the mechanisms that re-uptake dopamine in the pre-synaptic neuron.
Supposedly, individuals suffering from bipolar disorder tend to
overshoot resting levels of neurotransmitters, altrenating between manic and depressed phases.
I got zapped! I was very
exited after watching my football team win, and now
I am depressed for no reason.
I can't stand strip clubs. I find it too arousing, and I always get zapped the morning after.
Never
imbibe alcohol if you are depressed, or you will get zapped.